Quinta de São Luiz is located on the left bank of the River Douro, between Peso da Régua and Pinhão, in the parish of Adorigo, in the municipality of Tabuaço, in the heart of the Cima-Corgo sub-region.

When you reach Régua, head towards Pinhão on the EN222. Keep going straight until you see a sign on your right indicating the name of Quinta de São Luiz, just after the crossroads to Adorigo.

When you reach Pinhão, head towards Régua on the EN222. Keep going straight until you see a sign on your left indicating the name of Quinta de São Luiz, just after the crossroads to Tabuaço.